The best time to tackle weeding chores is right after irrigating or a rainfall. It's easiest to pull or dig weeds out in their entirety when the ground is soft.
To avoid feeling overwhelmed, tackle a small space every day, rotating throughout your garden. It's certainly easier to face weeding in small increments than it is to face weeding your entire yard.
After weeds are pulled or dug out, remove them entirely from the garden. Some weeds can grow back or go to seed if left where they are. Keep weeds out of the compost pile unless you are able to maintain heat high enough to kill any weed seeds. Most home compost piles don't get that hot.
For a simple, chemical-free way to kill vegetation, try boiling water. A tea kettle is an effective way to deliver a stream of heated water between the cracks of concrete or bricks. Just realize that everything the water touches will die from the heat, not just weeds.
Plant cover crops to reduce weeds. A cover crop, sometimes called green manure, is a fast-growing beneficial plant that outcompetes weeds for light and nutrients. Cover crops include wheat, barley, oats, rye, sorghum, and sudangrass. Some even release weed-suppressing natural chemicals while they're growing or decomposting. They can be planted any time during the growing season, then plowed or turned under when it's time to plant vegetables or flowers.